% =============================================================== % == Global Optimal Linearization of the nonlinear == % == dynamics of Mode 4 == % == == % == Supplement of the work: == % == == % == From Cardiac Cells to Genetic Regulatory Networks == % == == % == Description: == % == Compute the linear interpolation for the input == % == curve x,y. Output the coefficients error. == % == == % == Output: == % == xt: x intervals == % == a,b: segment coefficients == % == == % == Authors: == % == == % == R. Grosu, E. Bartocci == % == == % == Date: 11/05/10 == % == == % == Free distribution with authors permission == % == == % == SUNY Stony Brook, Stony Brook, NY == % == == % =============================================================== clear all; EPI_TVP = 1.4506; EPI_TV1M = 60.; EPI_TV2M = 1150.; EPI_TWP = 200.0; EPI_TW1M = 60.0; EPI_TW2M = 15.; EPI_TS1 = 2.7342; EPI_TS2 = 6.; EPI_TFI = 0.11; EPI_TO1 = 400.; EPI_TO2 = 6.; EPI_TSO1 = 30.0181; EPI_TSO2 = 0.9957; EPI_TSI = 1.8875; EPI_TWINF = 0.07; EPI_THV = 0.3; EPI_THVM = 0.006; EPI_THVINF = 0.006; EPI_THW = 0.13; EPI_THWINF = 0.006; EPI_THSO = 0.13; EPI_THSI = 0.13; EPI_THO = 0.006; EPI_KWM = 65.; EPI_KS = 2.0994; EPI_KSO = 2.0458; EPI_UWM = 0.03; EPI_US = 0.9087; EPI_UO = 0.; EPI_UU = 1.55; EPI_USO = 0.65; EPI_SC = 0.007; EPI_WINFSTAR = 0.94; % The same of Flavio's paper EPI_TW2M_TW1M = -45.0; EPI_TSO2_TSO1 = -29.0224; EPI_TW2M_TW1M_DIVBY2 = -22.5; EPI_TSO2_TSO1_DIVBY2 = -14.5112; %% Range from 0 and 1.5 x = linspace(0.3, 1.55, 1000); ds = ((1.+tanh(EPI_KS.*(x-EPI_US)))./2.); jfi = (x - EPI_THV) .* (EPI_UU - x)/EPI_TFI; jso = 1./(EPI_TSO1 + (EPI_TSO2_TSO1_DIVBY2).*(1.+tanh(EPI_KSO .*(x-EPI_USO)))); plot (x,[ds; jfi; jso]); ns = 14; [e,arange1,brange1,xrange1] = optimalLinearApproximation(x,[ds; jfi; jso],ns,1); a(1,1:ns) = arange1(1,ns,:); a(2,1:ns) = arange1(2,ns,:); a(3,1:ns) = arange1(3,ns,:); b(1,1:ns) = brange1(1,ns,:); b(2,1:ns) = brange1(2,ns,:); b(3,1:ns) = brange1(3,ns,:); xt = xrange1(ns, :);